Blue neural connections and golden symbolic pathways woven into a continuous feedback loop

Neuro-Symbolic Intelligence For Novel Formulations

The grand formulation challenge

Grounded enough
to work.
Novel enough
to matter.

Within an established field, new formulations can be grounded enough to work, yet offer only incremental gains in performance, cost or benefit.

Across disciplines, novel ideas offer the potential for remarkable gains. But few are grounded enough to succeed at the bench. Testing weak candidates is prohibitively expensive.

The challenge is to find both novelty and scientific grounding before committing resources to the lab.

Neural Exploration

A much wider field
of possibility.

The neural engine explores biology, chemistry, materials, excipients, actives and physics, building a candidate universe around your formulation challenge.

Neural exploration connects scientific knowledge with a formulation challenge to build a candidate universe. Neural exploration connects scientific knowledge with a formulation challenge to build a candidate universe.
Scientific knowledge spans biology, chemistry, materials, excipients, actives and physics. The neural engine explores and revisits this knowledge through a two-way exchange, guided by the formulation challenge, to build a candidate universe.

Neuro-Symbolic Discovery

Two forms of reasoning.
One continuous exchange.

Neural and symbolic engines work together on this candidate universe, continuously exchanging proposals and constraints to produce and rank eligible candidates.

Neural and symbolic engines jointly explore and evaluate the candidate universe to produce ranked eligible candidates. Neural and symbolic engines jointly explore and evaluate the candidate universe to produce ranked eligible candidates.
The candidate universe is worked on by both the neural and symbolic engines. A reciprocal exchange lets neural proposals inform symbolic evaluation and symbolic constraints guide further neural exploration. Together they produce and rank eligible candidates.

Symbolic Evaluation

Eligible candidates
to a focused shortlist.

The symbolic engine applies further scientific and formulation constraints to rank and refine eligible candidates into a shortlist for lab testing.

Further symbolic evaluation ranks and refines eligible candidates into a shortlist for lab testing. Further symbolic evaluation ranks and refines eligible candidates into a shortlist for lab testing.
Eligible candidates undergo further evaluation by the symbolic engine. Additional scientific and formulation constraints refine their ranking and narrow the shortlist that proceeds to lab testing.
Computational discovery, formulation work and partners collaborating beside pilot-production equipment

From discovery to the bench

from ai
discovery to
formulations

In our BioFormulation Lab, we create, test and refine shortlisted candidates against the original formulation challenge.

Create. Test. Refine.

Build with probio.science

What would you like
to make possible?

Bring us your next formulation challenge.

Let’s talk

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Explore the possibilities

Different applications.
Shared possibility.

Application areaEveryday NutritionAdvanced SkincareEdible PreservationAnimal Nutrition
FocusVitamins, minerals, probiotics, postbiotics, fibre and protein in one powder—with bitterness and off-tastes solved through advanced flavour masking.Oxidation and sticky handling—solved in an algae-derived formulation that makes these difficult lipids practical for skincare.Edible, healthy coatings for longer freshness. Expanding the possibilities across fish, meat, fruit, vegetables and fruit juice.Novel formulations for fish, shrimp and pets—bringing new possibilities to nutrition, feed performance and palatability.
Featured formulationEveryday nutritionBioCareBioShieldAnimal nutrition
Featured formulation stageProduction-readyEx vivo evaluatedCommercialCommercial